HLA sharing and history of miscarriage among women with rheumatoid arthritis
Journal Article
·
· American Journal of Human Genetics
OSTI ID:518562
- Univ. of Manchester Medical School (United Kingdom)
An increased frequency of recurrent spontaneous abortions (RSA), defined as three or more pregnancy losses without an identifiable cause, has been reported among women who share HLA alleles with their partner. A similar association has also been reported for women who have decreased fecundity. No specific HLA alleles have been identified as being the important etiological factor, raising the possibility that the observed sharing may represent a marker for sharing of other closely linked susceptibility genes. 12 refs., 1 tab.
- OSTI ID:
- 518562
- Journal Information:
- American Journal of Human Genetics, Vol. 60, Issue 3; Other Information: PBD: Mar 1997
- Country of Publication:
- United States
- Language:
- English
Similar Records
Sex influences on the penetrance of HLA shared-epitope genotypes for rheumatoid arthritis
Investigation of the HLA component involved in rheumatoid arthritis (RA) by using the marker association-segregation [chi][sup 2] (MASC) method: Rejection of the unifying-shared-epitope hypothesis
Reproductive failure and the major histocompatibility complex
Journal Article
·
Thu Feb 01 00:00:00 EST 1996
· American Journal of Human Genetics
·
OSTI ID:518562
Investigation of the HLA component involved in rheumatoid arthritis (RA) by using the marker association-segregation [chi][sup 2] (MASC) method: Rejection of the unifying-shared-epitope hypothesis
Journal Article
·
Wed Sep 01 00:00:00 EDT 1993
· American Journal of Human Genetics; (United States)
·
OSTI ID:518562
+4 more
Reproductive failure and the major histocompatibility complex
Journal Article
·
Thu Jun 01 00:00:00 EDT 1995
· American Journal of Human Genetics
·
OSTI ID:518562