Localization of the human transaldolase gene (TALDO) to chromosome 1p33-p34.1 by fluorescence in situ hybridization and PCR analysis of somatic cell hybrids

Journal Article · Sat Mar 01 00:00:00 EST 1997 · Genomics

DOI:https://doi.org/10.1006/geno.1996.4561· OSTI ID:518492

Kusuda, Jun; Hashimoto, Katusyuki ^[1]; Hirai, Momoki ^[2]

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1. National Inst. of Health, Tokyo (Japan)
2. Univ. of Tokyo (Japan); and others

Transaldolase catalyzes the transfer of a C3 fragment corresponding to dihydroxyacetone from sedoheptulose 7-phosphate to glyceraldehyde 3-phosphate, forming erythrose 4-phosphate and fructose 6-phosphate in the pentose phosphate pathway. The pathway provides mainly D-ribose 5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. 10 refs., 1 fig.

• OSTI ID: 518492
• Journal Information: Genomics, Vol. 40, Issue 2; Other Information: PBD: 1 Mar 1997
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
ALDOLASES
GENETIC MAPPING
GENE REGULATION
TISSUE DISTRIBUTION
DNA SEQUENCING
HUMAN CHROMOSOME 1
NUCLEIC ACIDS
BIOSYNTHESIS
LIPIDS
HEREDITARY DISEASES
ETIOLOGY
HUMAN CHROMOSOMES
FLUORESCENCE
IN-SITU HYBRIDIZATION
POLYMERASE CHAIN REACTION
SOMATIC CELLS
MYELIN
AMINO ACIDS
PROBES