Studies on a novel approach for the separation of L-phenylalanine amino acid from fermentation broth using a newly developed charged ultrafiltration membrane. I. Single solute system

Journal Article · Sat Jan 01 00:00:00 EST 1994 · Separation Science and Technology; (United States)

DOI:https://doi.org/10.1080/01496399408002476· OSTI ID:5184211

Agarwal, A K; Huang, R Y.M. ^[1]

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1. Univ. of Waterloo, Ontario (Canada)

A newly developed thin-film composite (TFC) ultrafiltration membrane made of sulfonated poly(phenylene oxide) (SPPO) was used to establish the feasibility of separating L-phenylalanine from the fermentation broth containing a number of dissolved inorganic and organic solutes as an alternative approach to the currently used complex and uneconomical conventional ion-exchange schemes. It was found that the rejection of inorganic salts in a single component system was highly dependent on the feed solution concentration and varied inversely with it. The pH of the feed solution was found to have a strong effect on the rejection of L-phenylalanine, changing it from - 10 to 90%. This rejection behavior was identical for the two TFC-SPPO membrane samples which had molecular weight cutoff ratings of 10,000 and 20,000, respectively, although the permeate flux of the latter sample was almost twice that of the former sample. It was found that glucose molecules were not rejected by the membrane. 11 refs., 18 figs., 2 tab.

• OSTI ID: 5184211
• Journal Information: Separation Science and Technology; (United States), Vol. 29:2; ISSN 0149-6395
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
PHENYLALANINE
ULTRAFILTRATION
COMPOSITE MATERIALS
FERMENTATION
GLUCOSE
MEMBRANES
MOLECULAR WEIGHT
ORGANIC POLYMERS
PH VALUE
SODIUM CHLORIDES
ALDEHYDES
ALKALI METAL COMPOUNDS
AMINO ACIDS
BIOCONVERSION
CARBOHYDRATES
CARBOXYLIC ACIDS
CHLORIDES
CHLORINE COMPOUNDS
FILTRATION
HALIDES
HALOGEN COMPOUNDS
HEXOSES
MATERIALS
MONOSACCHARIDES
ORGANIC ACIDS
ORGANIC COMPOUNDS
POLYMERS
SACCHARIDES
SEPARATION PROCESSES
SODIUM COMPOUNDS
400105* - Separation Procedures
400201 - Chemical & Physicochemical Properties