Design and analysis of an immobilized cell reactor with simultaneous product separation: ethanol from whey lactose

Thesis/Dissertation · Sat Jan 01 00:00:00 EST 1983

OSTI ID:5177728

Dale, M C

The simultaneous separation of volatile fermentation products from product inhibited fermentations can increase the productivity of a bioreactor by reducing the product concentration in the bioreactor. In this work, a simultaneous tubular reactor separator is developed in which the volatile product is removed from the reacting broth by an inert gas phase. The immobilized cell reactor separator (ICRS) consists of two column reactors: a cocurrent enriching column followed by an countercurrent stripping column. The application of the ICRS concept to the ethanol from whey lactose fermentation was investigated using the yeast Kluyveromyces fragilis 2415. An equilibrium stage model of the ICRS was developed including a surface renewal term for an adsorbed monolayer of reacting cells. This model demonstrated the effect of important operational parameters including temperature, pressure, and gas flow rates. Experimental results using yeast adsorbed to 1/4'' ceramic saddles were somewhat unsatisfactory but very high productivities, cell densities, and separation efficiency were obtained using an absorbant column packing in a gas continuous operating mode.

• Research Organization: Purdue Univ., Lafayette, IN (USA)
• OSTI ID: 5177728
• Resource Relation: Other Information: Thesis (Ph.D.)
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
09 BIOMASS FUELS
BIOREACTORS
DESIGN
LACTOSE
FERMENTATION
SEPARATION PROCESSES
ADSORPTION
ETHANOL
IMMOBILIZED CELLS
WHEY
YEASTS
ALCOHOLS
BIOCONVERSION
CARBOHYDRATES
DISACCHARIDES
FUNGI
HYDROXY COMPOUNDS
INDUSTRIAL WASTES
MICROORGANISMS
OLIGOSACCHARIDES
ORGANIC COMPOUNDS
PLANTS
SACCHARIDES
SORPTION
WASTES
550700* - Microbiology
090222 - Alcohol Fuels- Preparation from Wastes or Biomass- (1976-1989)