Computerized scintigraphic technique for the evaluation of adult respiratory distress syndrome: initial clinical trials

Journal Article · Thu Apr 01 00:00:00 EST 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.143.1.6461025· OSTI ID:5176712

Tatum, J L; Burke, T S; Sugerman, H J; Strash, A M; Hirsch, J I; Fratkin, M J

Eleven patients with suspected adult respiratory distress syndrome (ARDS) and five control patients were studied using a computerized gamma imaging and analysis technique and 99mTc-labeled human serum albumin. The heart and right lung were imaged, lung:heart ratio was plotted vs. time, and a linear regression was fitted to the data points displayed. The slope of this fit was termed the ''slope index.'' An index value of 2 standard deviations greater than the control mean was considered positive. Radiographs from the six positive studies revealed typical diffuse air-space disease. Radiographs from two of the five negative studies demonstrated air-space consolidation. Both of these patients had elevated pulmonary capillary wedge pressure, cardiomegaly, and clinical course consistent with cardiogenic pulmonary edema. These preliminary data demonstrated a good correlation between positive slope index and clinical ARDS.

• Research Organization: Department of Radiology, Virginia Commonwealth University, Richmond
• OSTI ID: 5176712
• Journal Information: Radiology; (United States), Vol. 143:1
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
HEART
SCINTISCANNING
LUNGS
RESPIRATORY SYSTEM DISEASES
DIAGNOSIS
TECHNETIUM 99
ALBUMINS
ELDERLY PEOPLE
ISOMERIC NUCLEI
PATIENTS
AGE GROUPS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
HOURS LIVING RADIOISOTOPES
HUMAN POPULATIONS
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MINORITY GROUPS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
POPULATIONS
PROTEINS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
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