Cognitive performance effects of low zinc (Zn) intakes in healthy adult men
- Dept. of Agriculture, Grand Forks, ND (United States)
A battery of tasks assessing sensory-motor skills and cognitive performance was administered to 14 healthy men participating in a 7-month, live-in metabolic study of Zn nutrition. Following a 33-day equilibration period, during which Zn intake was approximately 10 mg/2,500 kcal/day, all subjects were fed 1, 2, 3, or 4 mg Zn/day during each of four consecutive 35-day depletion periods administered in a random, double-blind manner. The study concluded with a 35-day repletion period providing 10 mg Zn/day. When contrasted with performance during the Zn repletion period, measures of response time and/or error on 10 of the 15 tasks administered showed a significant negative relationship to dietary Zn intake. Two sensory-motor tasks, two attention tasks, three perceptual tasks, two memory tasks, and one spatial task showed impaired performance with the low Zn intakes. However, there were few differences among the four depletion periods to support a dose effect of dietary Zn. Results suggest that even marginally low Zn intakes may have a negative effect on psychological and behavioral function in otherwise healthy young adult men.
- OSTI ID:
- 5174374
- Report Number(s):
- CONF-9104107-; CODEN: FAJOE
- Journal Information:
- FASEB Journal (Federation of American Societies for Experimental Biology); (United States), Vol. 5:5; Conference: 75. annual meeting of the Federation of American Societies for Experimental Biology (FASEB), Atlanta, GA (United States), 21-25 Apr 1991; ISSN 0892-6638
- Country of Publication:
- United States
- Language:
- English
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