Utilization of 3-D elastic transformation in the registration of chest x-ray CT and whole body PET

Conference · Tue Dec 31 00:00:00 EST 1996

OSTI ID:513318

Tai, Yuan-Chuan; Hoh, C K; Hoffman, E J ^[1]

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1. UCLA School of Medicine, Los Angeles, CA (United States); and others

X-ray CT is widely used for detection and localization of lesions in the thorax. Whole Body PET with 18-FDG is becoming accepted for staging of cancer because of its ability to detect malignancy. Combining information from these two modalities has a significant value to improve lung cancer staging and treatment planning. Due to the non-rigid nature of the thorax and the differences in the acquisition conventions, the subject is stretched non-uniformly and the images of these two modalities requires non-rigid transformation for proper registration. Techniques to register chest x-ray CT and Whole Body PET images were developed and evaluated. Accuracy of 3-D elastic transformation was tested by phantom study. Studies on patients with lung carcinoma were used to validate the technique in localizing the 18-FDG uptake and in correlating PET to x-ray CT images. The fused images showed an accurate alignment and provided confident identification of the detailed anatomy of the CT with the functional information of the PET images.

• DOE Contract Number: FC03-87ER60615
• OSTI ID: 513318
• Report Number(s): CONF-961123-; CNN: Grant R01-CA56655; TRN: 97:014370
• Resource Relation: Conference: Institute of Electrical and Electronic Engineers (IEEE) nuclear science symposium and medical imaging conference, Anaheim, CA (United States), 2-9 Nov 1996; Other Information: PBD: 1996; Related Information: Is Part Of 1996 IEEE nuclear science symposium - conference record. Volumes 1, 2 and 3; Del Guerra, A. [ed.]; PB: 2138 p.
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
44 INSTRUMENTATION
INCLUDING NUCLEAR AND PARTICLE DETECTORS
99 MATHEMATICS
COMPUTERS
INFORMATION SCIENCE
MANAGEMENT
LAW
MISCELLANEOUS
POSITRON COMPUTED TOMOGRAPHY
IMAGE PROCESSING
PHOTON COMPUTED TOMOGRAPHY
BODY
CHEST
TRANSFORMATIONS
X-RAY RADIOGRAPHY
THREE-DIMENSIONAL CALCULATIONS
LUNGS
NEOPLASMS