Pulsed holmium laser ablation of cardiac valves

Journal Article · Sun Jan 01 00:00:00 EST 1989 · Lasers in Surgery and Medicine; (USA)

DOI:https://doi.org/10.1002/lsm.1900090506· OSTI ID:5127882

Lilge, L; Radtke, W; Nishioka, N S ^[1]

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1. Massachusetts General Hospital, Boston (USA)

Ablation efficiency and residual thermal damage produced by pulsed holmium laser radiation were investigated in vitro for bovine mitral valves and human calcified and noncalcified cardiac valves. Low-OH quartz fibers (200 and 600 microns core diameter) were used in direct contact perpendicular to the specimen under saline or blood. Etch rate was measured with a linear motion transducer. Radiant exposure was varied from 0 to 3 kJ/cm{sup 2}. For 200-microns fibers, the energy of ablation was approximately 5 kJ/cm{sup 3} in noncalcified and 15 kJ/cm{sup 3} in calcified valves. Etch rates were dependent on mechanical tissue properties. Maximum etch rate at 1,000 J/cm{sup 2} was 1-2 mm/pulse at 3 Hz repetition rate. Microscopic examination revealed a zone of thermal damage extending 300 microns lateral into adjacent tissue. Thermal damage was independent of radiant exposure beyond twice threshold.

• OSTI ID: 5127882
• Journal Information: Lasers in Surgery and Medicine; (USA), Vol. 9:5; ISSN 0196-8092
• Country of Publication: United States
• Language: English

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AORTA
CALCINOSIS
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CARDIOVASCULAR DISEASES
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