Molecular approaches to human polygenic disease - Symposium 130

Book · Thu Jan 01 00:00:00 EST 1987

OSTI ID:5087114

This volume deals with the application of recombinant DNA techniques to the identification of diseases that have more than one inherited component. Focus is on the polygenic factors responsible for coronary atherosclerosis. Several other disorders having a polygenic orgin are also discussed, including hypertension, diabetes mellitus, psychiatric diseases, and autoimmune (HLA-related) disorders. Problems raised by the study of different families or different populations are covered, as well as the possibility of applying molecular techniques to disease prevention-for example, through gene therapy. Also explored are some of the ethical issues that relate to human gene mapping.

• OSTI ID: 5087114
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
09 BIOMASS FUELS
HEREDITARY DISEASES
MOLECULAR BIOLOGY
MAN
GENETIC MAPPING
RECOMBINANT DNA
TECHNOLOGY ASSESSMENT
ARTERIOSCLEROSIS
BIOTECHNOLOGY
CORONARIES
DIABETES MELLITUS
ETHICAL ASPECTS
ETIOLOGY
GENETIC ENGINEERING
HYPERTENSION
IMMUNOLOGY
LEADING ABSTRACT
PREVENTIVE MEDICINE
PSYCHOLOGY
ABSTRACTS
ANIMALS
ARTERIES
BLOOD VESSELS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
DISEASES
DNA
DOCUMENT TYPES
ENDOCRINE DISEASES
MAMMALS
MAPPING
MEDICINE
METABOLIC DISEASES
NUCLEIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PRIMATES
SYMPTOMS
VASCULAR DISEASES
VERTEBRATES
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