Organic ion imaging using tandem mass spectrometry
- Oak Ridge National Lab., TN (United States); and others
A triple-quadrupole mass spectrometer has been interfaced with a wide-angle secondary ion microprobe. The combination permits acquisition of data necessary to determine the distribution of targeted organic analytes even in the presence of overwhelming isobaric interference. Micrographs generated from secondary ion intensity alone are compared to those generated using secondary ionization with tandem mass spectrometry (MS/MS), both for image reference and to show the improvement in image quality that can be attained when MS/MS is employed. Inhomogeneous mixtures of glycerol, KCl, and asparagine on 1-cm-diameter aluminum targets were used to demonstrate the instrument`s selectivity. Secondary ions generated from samples of this system include isobaric {sup 133}Cs{sup +} implanted from the primary ion beam, the {sup 41}K{sup +} -glycerol adduct, and protonated asparagine. 30 refs., 9 figs., 1 tab.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 508615
- Journal Information:
- Analytical Chemistry (Washington), Vol. 64, Issue 17; Other Information: PBD: 1 Sep 1992
- Country of Publication:
- United States
- Language:
- English
Similar Records
Utilizing metal cation reactions with carbonyl sulfide to remove isobaric interferences in tandem inductively coupled plasma mass spectrometry analyses
Laser photodissociation/tandem mass spectrometry of synthetic porphyrins: a structural probe