Malignant thyroid tumors after iodine-131 therapy
We studied the incidence of malignant thyroid tumors after /sup 131/l therapy in 2727 patients with hyperthyroidism and in 273 euthyroid patients with cardiac disease. The patients were all adults, with a mean age of 57 years. The /sup 131/l therapy was given between 1951 and 1965. The mean follow-up period was 13 years for the hyperthyroid patients (15 years for the 85 per cent surviving for more than five years) and six years for the cardiac patients (12 years for the 41 per cent surviving for more than five years). The incidence of malignant thyroid tumors was based on a search of the Swedish Cancer Registry for the occurrence of such tumors in any of the 3000 patients. At present there is no increased incidence of malignant thyroid tumors after /sup 131/l therapy (four cases observed versus 3.2 cases expected).
- OSTI ID:
- 5059496
- Journal Information:
- New Engl. J. Med.; (United States), Vol. 303:4
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
NEOPLASMS
INTERNAL IRRADIATION
RADIOINDUCTION
RADIOTHERAPY
SIDE EFFECTS
THYROID
BIOLOGICAL RADIATION EFFECTS
CARDIOVASCULAR DISEASES
HYPERTHYROIDISM
IODINE 131
MEDICAL SURVEILLANCE
PATIENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
IRRADIATION
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIATION EFFECTS
RADIOISOTOPES
RADIOLOGY
THERAPY
560161* - Radionuclide Effects
Kinetics
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550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)