Effect of parents occupational exposures on risk of stillbirth, preterm delivery, and small-for-gestational-age in infants

Journal Article · Thu Jun 01 00:00:00 EDT 1989 · American Journal of Epidemiology; (USA)

OSTI ID:5029477

Savitz, D A; Whelan, E A; Kleckner, R C ^[1]

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1. Univ. of North Carolina, Chapel Hill (USA)

Epidemiologic research on the effects of parental occupational exposures on fetal development has been limited. The National Natality and Fetal Mortality surveys obtained applicable data of probability samples of live births and fetal deaths which occurred in the US in 1980 among married women. Analyses were conducted for case groups of stillbirths (2,096 mothers, 3,170 fathers), preterm deliveries (<37 weeks completed gestation) (363 mothers, 552 fathers), and small-for gestational-age infants (218 mothers, 371 fathers) compared with controls. Occupational exposures were defined by industry of employment and by imputed exposures based on a job-exposure linkage system. For stillbirth, maternal work in the rubber, plastics, and synthetics industry and lead exposure and paternal employment in the textile industry had the largest odds ratios. Preterm birth was most strongly associated with maternal lead exposure, corroborating previous findings. Twofold increased risk of preterm delivery was found with paternal employment in the glass, clay, and stone; textile; and mining industries. Paternal exposures to x-rays and polyvinyl alcohol were associated with 1.5-fold increase in risk. The occupation of the mother was not associated with delivery of a small-for-gestational-age infant, in contrast to paternal employment in the art and textile industries. Several toxic agents were associated with risk elevation of 1.3 or greater for fathers, most notably benzene.

• OSTI ID: 5029477
• Journal Information: American Journal of Epidemiology; (USA), Vol. 129:6; ISSN 0002-9262
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BENZENE
HEALTH HAZARDS
LEAD
MINING
SOLVENTS
X RADIATION
RADIATION HAZARDS
BIOMEDICAL RADIOGRAPHY
EPIDEMIOLOGY
FETUSES
INDUSTRIAL PLANTS
MEN
MORTALITY
MUTAGENESIS
OCCUPATIONAL EXPOSURE
PRENATAL EXPOSURE
PVA
REPRODUCTIVE DISORDERS
RISK ASSESSMENT
WOMEN
ALCOHOLS
ANIMALS
AROMATICS
DIAGNOSTIC TECHNIQUES
ELECTROMAGNETIC RADIATION
ELEMENTS
FEMALES
HAZARDS
HYDROCARBONS
HYDROXY COMPOUNDS
IONIZING RADIATIONS
MALES
MAMMALS
MAN
MEDICINE
METALS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANIC POLYMERS
POLYMERS
POLYVINYLS
PRIMATES
RADIATIONS
RADIOLOGY
VERTEBRATES
560300* - Chemicals Metabolism &amp; Toxicology
560151 - Radiation Effects on Animals- Man