Na{sup +}/H{sup +} exchanger-1 alleles: Strain distribution and correlation with activity
Journal Article
·
· Immunogenetics
OSTI ID:501873
- Walter and Eliza Hall Inst. of Medical Research, Parkville, Victoria (Australia)
- Baker Medical Research Inst., Victoria (Australia)
The Na{sup +}/H{sup +} exchanger-1 molecule (NHE1) regulates intracellular pH, cell volume, and cell growth. NHE1 is a phosphoprotein of approximately M{sub r} 110000 with 10 or 12 transmembrane domains. NHE1 is ubiquitously expressed. Three other family members have been identified which show close similarity to NHE1 but are significantly more restricted in their expression: all are found in the gastrointestinal tract, while NHE2 and NHE3 are also expressed in the kidney. 14 refs., 2 figs.
- OSTI ID:
- 501873
- Journal Information:
- Immunogenetics, Vol. 43, Issue 3; Other Information: PBD: 1996
- Country of Publication:
- United States
- Language:
- English
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