Implications of abnormal right ventricular thallium uptake in acute myocardial infarction
The correlates of abnormal right ventricular (RV) thallium uptake were examined in 116 patients with documented acute myocardial infarction (AMI) who underwent predischarge thallium-201 scintigraphy at rest, radionuclide angiography and 24-hour ambulatory electrocardiography. The patients were separated into 2 groups: patients group 1 (n = 31) had increased RV thallium uptake and those in group 2 (n = 85) had no such uptake. The 2 groups were comparable in age, type and site of AMI, peak creatine kinase level, systolic blood pressure and heart rate. However, compared with group 2, group 1 had a lower mean left ventricular (LV) ejection fraction (33 +/- 15% vs 39 +/- 14%, p less than 0.05), higher prevalence of increased lung thallium uptake (45% vs 22%, p less than 0.02), more extensive LV perfusion defects (4.4 +/- 2.9 vs 3.0 +/- 3.0 segments, p less than 0.03) and more complex ventricular arrhythmias (55% vs 35%, p less than 0.05). At a mean follow-up of 6 months, 17 patients (8 in group 1 and 9 in group 2) died from cardiac causes. Actuarial life-table analysis showed that the survival rate was better in group 2 than in group 1 (Mantel-Cox statistics = 4.62, p = 0.03). Thus, patients with AMI and abnormal RV thallium uptake have worse LV function, more complex ventricular arrhythmias and worse prognosis.
- Research Organization:
- Hahnemann Univ., Philadelphia, PA
- OSTI ID:
- 5017893
- Journal Information:
- Am. J. Cardiol.; (United States), Vol. 3
- Country of Publication:
- United States
- Language:
- English
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HEART
SCINTISCANNING
THALLIUM 201
UPTAKE
BIOMEDICAL RADIOGRAPHY
BLOOD PRESSURE
MYOCARDIAL INFARCTION
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BETA DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
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DIAGNOSTIC TECHNIQUES
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ELECTRON CAPTURE RADIOISOTOPES
HEAVY NUCLEI
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550601* - Medicine- Unsealed Radionuclides in Diagnostics