Surface morphology and functional studies of human alveolar macrophages from cigarette smokers and nonsmokers

Journal Article · Fri Jan 01 00:00:00 EST 1982 · RES, J. Reticuloendothel. Soc.; (United States)

OSTI ID:5011708

Finch, G L ^[1]; Fisher, G L; Hayes, T L; Golde, D W

---

1. Univ. of California, Berkeley

The surface of macrophages inhabiting the peritoneal and alveolar spaces is pleomorphic in structure. The internal structure of these cells has been widely described and is not discussed here. Although external cell morphology has been well characterized by many researchers, this subject has not been reviewed. This review, therefore, describes in detail the surface features of macrophages as well as factors affecting macrophage morphology. Morphological studies of human cells are emphasized. Functional studies are presented and, when possible, morphological parameters are correlated with cell function. Because cigarette smoking has been well studied, the effects of this pulmonary insult are described in detail.

• DOE Contract Number: W-7405-ENG-48
• OSTI ID: 5011708
• Journal Information: RES, J. Reticuloendothel. Soc.; (United States), Vol. 32
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
ANESTHETICS
BIOLOGICAL EFFECTS
LYSOSOMES
SCANNING ELECTRON MICROSCOPY
MACROPHAGES
MORPHOLOGY
TOBACCO SMOKES
CELL CULTURES
LAVAGE
MAN
PHAGOCYTOSIS
AEROSOLS
ANIMAL CELLS
ANIMALS
CELL CONSTITUENTS
CENTRAL NERVOUS SYSTEM DEPRESSANTS
COLLOIDS
CONNECTIVE TISSUE CELLS
DISPERSIONS
DRUGS
ELECTRON MICROSCOPY
MAMMALS
MICROSCOPY
ORGANOIDS
PHAGOCYTES
PRIMATES
RESIDUES
SMOKES
SOLS
SOMATIC CELLS
VERTEBRATES
550800* - Morphology
550300 - Cytology