Radioisotope labeled platelets in medical diagnosis

Journal Article · Fri Aug 01 00:00:00 EDT 1986 · Invest. Radiol.; (United States)

DOI:https://doi.org/10.1097/00004424-198608000-00002· OSTI ID:5007690

Pope, C F; Sostman, H D

The myriad of applications of indium-111 labeled platelets (/sup 111/In-P), both in biomedical research and clinical diagnostic imaging, in recent years is an index of the potential of this technology. Because many diseases involve the vascular system, a nontoxic platelet label suitable for imaging has immense potential for diagnosis. Presently confined to research centers, this technique is currently used in three main diagnostic situations: deep vein thrombosis, cardiac thrombi, and organ (renal) transplantation rejection. Future applications will proliferate when difficulties in achieving rapid labeling are overcome, and the period between study initiation and final diagnosis is diminished. This review emphasizes current clinical applications and the potential role of this technology in diagnostic imaging. 52 references.

• Research Organization: Yale Univ. School of Medicine, New Haven, CT
• OSTI ID: 5007690
• Journal Information: Invest. Radiol.; (United States), Vol. 8
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD PLATELETS
DIAGNOSTIC USES
CARDIOVASCULAR DISEASES
DIAGNOSIS
EMBOLI
GRAFT-HOST REACTION
INDIUM 111
KIDNEYS
LABELLED COMPOUNDS
MYOCARDIAL INFARCTION
RADIOISOTOPE SCANNING
THROMBOSIS
TRANSPLANTS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
USES
VASCULAR DISEASES
550601* - Medicine- Unsealed Radionuclides in Diagnostics