Immunoassay as a screening tool for industrial toxicants

Journal Article · Fri Aug 01 00:00:00 EDT 1986 · JOM, J. Occup. Med.; (United States)

DOI:https://doi.org/10.1097/00043764-198608000-00013· OSTI ID:5000850

Pierce, T

Immunoassay techniques may represent useful screening tools to assist analysts interested in the presence and amounts of organic toxicants in biological fluids. The widespread application of immunoassay methods in medicinal and forensic (drugs of abuse) chemistry has resulted in such screening methodologies. Four methodologies of potential benefit are considered: the free radical assay technique, the enzyme-mediated immunoassay technique, radioimmunoassay, and hemagglutination. Each of these immunoassays is based on the competitive displacement of the labeled drug (or toxicant) from the antibody complex by the unlabeled drug-toxicant in the sample.

• Research Organization: Univ. of North Alabama, Florence
• OSTI ID: 5000850
• Journal Information: JOM, J. Occup. Med.; (United States), Vol. 8
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
HAZARDOUS MATERIALS
RADIOIMMUNOASSAY
BIOLOGICAL INDICATORS
HUMAN POPULATIONS
MONITORING
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
MATERIALS
POPULATIONS
RADIOASSAY
RADIOIMMUNOLOGY
TRACER TECHNIQUES
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)