Genetic and physical mapping of a voltage-dependent chloride channel gene to human 4q32 and to mouse 8
- Univ. of Iowa Hospitals and Clinics, Iowa City, IA (United States)
- Fox Chase Cancer Center, Philadelphia, PA (United States); and others
This report describes the localization of a gene encoding a voltage-dependent chloride channel to human chromosome 4q32 and to mouse chromosome 8 using fluorescence in situ hybridization. Mutations in these voltage-gated chloride channel genes have been implicated in various hereditary diseases. 14 refs., 1 fig.
- OSTI ID:
- 486330
- Journal Information:
- Genomics, Vol. 36, Issue 2; Other Information: PBD: 1 Sep 1996
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
55 BIOLOGY AND MEDICINE
BASIC STUDIES
PORINS
GENETIC MAPPING
GENE REGULATION
DNA SEQUENCING
TISSUE DISTRIBUTION
GENE MUTATIONS
CHROMOSOMES
HUMAN CHROMOSOMES
MAN
NERVOUS SYSTEM DISEASES
HEREDITARY DISEASES
MICE
CHLORIDES
SOMATIC CELLS
HYBRIDIZATION
BANDING TECHNIQUES
DNA HYBRIDIZATION
FLUORESCENCE
POLYMERASE CHAIN REACTION
BIOLOGICAL MARKERS
BASIC STUDIES
PORINS
GENETIC MAPPING
GENE REGULATION
DNA SEQUENCING
TISSUE DISTRIBUTION
GENE MUTATIONS
CHROMOSOMES
HUMAN CHROMOSOMES
MAN
NERVOUS SYSTEM DISEASES
HEREDITARY DISEASES
MICE
CHLORIDES
SOMATIC CELLS
HYBRIDIZATION
BANDING TECHNIQUES
DNA HYBRIDIZATION
FLUORESCENCE
POLYMERASE CHAIN REACTION
BIOLOGICAL MARKERS