Instrument for the application of controlled mechanical loads to tissues in sterile culture
Apparatus and methods are disclosed facilitating the application of forces and measurement of dimensions of a test subject. In one arrangement the test subject is coupled to a forcing frame and controlled forces applied thereto by a series of guideways and sliders. The sliders, which contact the test subject are in force transmitting relation to a forcing frame. Tension, compression and bending forces can be applied to the test subject. Force applied to the test subject is measured and controlled. A dimensional characteristic of the test subject, such as growth, is measured by a linear variable differential transformer. The growth measurement data can be used to control the force applied. Substantially uniaxial stretching is achieved by placing the test subject on an elastic membrane stretched by an arrangement of members securing the elastic member to the forcing frame. 8 figs.
- Research Organization:
- Liveco Inc
- DOE Contract Number:
- AC02-86ER80373
- Assignee:
- John Chatillon and Sons, Inc., Greensboro, NC (United States)
- Patent Number(s):
- US 5,406,853/A/
- Application Number:
- PAN: 8-082,064
- OSTI ID:
- 46304
- Resource Relation:
- Other Information: PBD: 18 Apr 1995
- Country of Publication:
- United States
- Language:
- English
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Instrument for controlling the application of mechanical loads to biological and bicompatible test subjects
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