Linkage results in Schizophrenia
Journal Article
·
· American Journal of Medical Genetics
- Columbia Univ. College of Physicians and Surgeons, New York, NY (United States)
In setting a model for replication studies, the collective effort by the various investigators is praiseworthy. The linkage reported is intriguing, but given the aforementioned caveats it would be premature to dub it {open_quotes}significant -- and, probably, confirmed.{close_quotes} The extent to which a real genetic effect exists on chromosome 6p24-22 remains to be seen. Compelling confirmation, which further study might proffer, would be a welcome boost to a fledgling enterprise, where other findings of promise have faltered or failed to gain unequivocal support. The caution advised in this commentary may guide the design and interpretation of other linkage studies in psychiatric disorders.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 447653
- Journal Information:
- American Journal of Medical Genetics, Vol. 67, Issue 2; Other Information: PBD: 9 Apr 1996
- Country of Publication:
- United States
- Language:
- English
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