Inhibition by progesterone of radiation-estrogen-induced mammary cancer in the rat
Journal Article
·
· Cancer Res., v. 33, no. 5, pp. 1136-1137
OSTI ID:4365356
The data from this preliminary experiment make it appear that continuous administration of progesterone protects animals from the synergism between estrogen and radiation. However, it also appears that the progesterone has by itself a protective effect against the individual carcinogenic agents since fewer tumors occurred on the opposite side as well as on the radiated side. In this preliminary experiment none of the animals that bore just progesterone pellets and were radiated developed mammary carcinomata. (auth)
- Research Organization:
- Alton Ochsner Medical Foundation, New Orleans
- NSA Number:
- NSA-29-008011
- OSTI ID:
- 4365356
- Journal Information:
- Cancer Res., v. 33, no. 5, pp. 1136-1137, Other Information: Orig. Receipt Date: 30-JUN-74
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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Related Subjects
N48520* -Life Sciences-Radiation Effects on Animals- Vertebrates
*ESTROGENS- CARCINOGENESIS
*NEOPLASMS- RADIOINDUCTION
*PROGESTERONE- RADIOSENSITIVITY EFFECTS
BIOLOGICAL RADIATION EFFECTS
IONIZING RADIATIONS
MAMMARY GLANDS
PARTIAL BODY IRRADIATION
RADIOSENSITIVITY EFFECTS
RATS
RESPONSE MODIFYING FACTORS
SYNERGISM RADIOINDUCTION
*ESTROGENS- CARCINOGENESIS
*NEOPLASMS- RADIOINDUCTION
*PROGESTERONE- RADIOSENSITIVITY EFFECTS
BIOLOGICAL RADIATION EFFECTS
IONIZING RADIATIONS
MAMMARY GLANDS
PARTIAL BODY IRRADIATION
RADIOSENSITIVITY EFFECTS
RATS
RESPONSE MODIFYING FACTORS
SYNERGISM RADIOINDUCTION