Fundamental and clinical studies on tumor control by TBI

Journal Article · Tue Dec 31 00:00:00 EST 1996 · Transactions of the American Nuclear Society

OSTI ID:426552

Sakamoto, Kiyohiko ^[1]; Myojin, Miyako ^[2]

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1. Tohoku Univ., Sendai (Japan)
2. Sapporo National Hospital, Iroishi (Japan)

Total body irradiation (TBI) has been considered to bring about immunosuppressive effects on organisms. The conclusion is derived from data obtained by sublethal doses of TBI, but there are no data on how low doses of TBI act on organisms. On the other hand, it is known that low doses of TBI are effective on some malignant lymphoma or chronic myelogenous leukemia. However, the effect of low doses of TBI is rarely investigated radiobiologically. For 15 yr, the authors have studied the effects of low doses of TBI on normal or tumor-bearing mice and its immunological background. In this paper, they show the results of fundamental and clinical studies on tumor control by low doses of TBI.

• OSTI ID: 426552
• Report Number(s): CONF-961103-; ISSN 0003-018X; TRN: 96:006307-0284
• Journal Information: Transactions of the American Nuclear Society, Vol. 75; Conference: Winter meeting of the American Nuclear Society (ANS) and the European Nuclear Society (ENS), Washington, DC (United States), 10-14 Nov 1996; Other Information: PBD: 1996
• Country of Publication: United States
• Language: English

Related Subjects

56 BIOLOGY AND MEDICINE
APPLIED STUDIES
MICE
WHOLE-BODY IRRADIATION
NEOPLASMS
RADIOTHERAPY
LOW DOSE IRRADIATION
THERAPEUTIC USES