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Title: Long-term exposure of adults to outdoor air pollution is associated with increased airway obstruction and higher prevalence of bronchial hyperresponsiveness

Abstract

The authors studied the association between long-term exposure to outdoor air pollution and the severity of obstructive pulmonary disease and prevalence of bronchial hyperreactivity to {beta}2 agonists in two groups of adult patients who were of similar ages and who had similar smoking habits. The subjects lived in downtown districts or in the outer suburbs of Marseilles, the neighborhood that contained air samplers. The regions were similar with respect to sulfur dioxide levels, but levels of nitric oxides and particulate matter were higher in the downtown area than the suburbs. The authors assessed airway obstruction, as determined by a decrease in forced expiratory volume in 1 s, mean forced expiratory flow measured between 25% and 75% of vital capacity, and an elevated value of central airway resistance. The authors tested the changes in these variables induced by inhalation of a {beta}2 agonist. Baseline lung function was altered more significantly in both male and female patients who lived in downtown Marseilles than in those who resided in the suburbs, and the differences persisted regardless of the season during which the study occurred. Prevalence of bronchial hyperreactivity and symptoms of asthma were higher in the downtown than suburban male subjects. The resultsmore » of this study suggest that an association exists between actual environmental exposure to outdoor air pollution and respiratory effects in sensitive adults represented by patients with chronic obstructive pulmonary disease or asthma.« less

Authors:
; ;  [1]; ;  [2]
  1. Univ. de la Mediterranee, Marseilles (France)
  2. Hopital Nord et, Marseilles (France). Lab. des Explorations Fonctionnelles
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
330518
Resource Type:
Journal Article
Journal Name:
Archives of Environmental Health
Additional Journal Information:
Journal Volume: 53; Journal Issue: 6; Other Information: PBD: Nov-Dec 1998
Country of Publication:
United States
Language:
English
Subject:
54 ENVIRONMENTAL SCIENCES; 56 BIOLOGY AND MEDICINE, APPLIED STUDIES; AIR POLLUTION; AIR POLLUTION MONITORING; HEALTH HAZARDS; RESPIRATORY SYSTEM DISEASES; FRANCE; SULFUR DIOXIDE; NITRIC OXIDE; PARTICULATES; ADULTS; CHRONIC EXPOSURE

Citation Formats

Jammres, Y, Delpierre, S, Burnet, H, Delvolgo, M J, and Humbert-Tena, C. Long-term exposure of adults to outdoor air pollution is associated with increased airway obstruction and higher prevalence of bronchial hyperresponsiveness. United States: N. p., 1998. Web. doi:10.1080/00039899809605723.
Jammres, Y, Delpierre, S, Burnet, H, Delvolgo, M J, & Humbert-Tena, C. Long-term exposure of adults to outdoor air pollution is associated with increased airway obstruction and higher prevalence of bronchial hyperresponsiveness. United States. https://doi.org/10.1080/00039899809605723
Jammres, Y, Delpierre, S, Burnet, H, Delvolgo, M J, and Humbert-Tena, C. 1998. "Long-term exposure of adults to outdoor air pollution is associated with increased airway obstruction and higher prevalence of bronchial hyperresponsiveness". United States. https://doi.org/10.1080/00039899809605723.
@article{osti_330518,
title = {Long-term exposure of adults to outdoor air pollution is associated with increased airway obstruction and higher prevalence of bronchial hyperresponsiveness},
author = {Jammres, Y and Delpierre, S and Burnet, H and Delvolgo, M J and Humbert-Tena, C},
abstractNote = {The authors studied the association between long-term exposure to outdoor air pollution and the severity of obstructive pulmonary disease and prevalence of bronchial hyperreactivity to {beta}2 agonists in two groups of adult patients who were of similar ages and who had similar smoking habits. The subjects lived in downtown districts or in the outer suburbs of Marseilles, the neighborhood that contained air samplers. The regions were similar with respect to sulfur dioxide levels, but levels of nitric oxides and particulate matter were higher in the downtown area than the suburbs. The authors assessed airway obstruction, as determined by a decrease in forced expiratory volume in 1 s, mean forced expiratory flow measured between 25% and 75% of vital capacity, and an elevated value of central airway resistance. The authors tested the changes in these variables induced by inhalation of a {beta}2 agonist. Baseline lung function was altered more significantly in both male and female patients who lived in downtown Marseilles than in those who resided in the suburbs, and the differences persisted regardless of the season during which the study occurred. Prevalence of bronchial hyperreactivity and symptoms of asthma were higher in the downtown than suburban male subjects. The results of this study suggest that an association exists between actual environmental exposure to outdoor air pollution and respiratory effects in sensitive adults represented by patients with chronic obstructive pulmonary disease or asthma.},
doi = {10.1080/00039899809605723},
url = {https://www.osti.gov/biblio/330518}, journal = {Archives of Environmental Health},
number = 6,
volume = 53,
place = {United States},
year = {Sun Nov 01 00:00:00 EST 1998},
month = {Sun Nov 01 00:00:00 EST 1998}
}