skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: The CEPH consortium linkage map of human chromosome 13

Abstract

The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158, 203, and 178cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM. 76 refs., 3 figs., 5 tabs.

Authors:
;  [1]; ;  [2];  [3]; ; ;  [4];  [5];  [6]
  1. Univ. of Texas Southwestern Medical Center, Dallas, TX (United States)
  2. Univ. of Utah School of Medicine, Salt Lake City, UT (United States)
  3. Univ. of Iowa, Iowa City, IA (United States)
  4. Johns Hopkins School of Medicine, Baltimore, MD (United States)
  5. Univ. of Stellenbosch, Tygerberg (South Africa)
  6. Centre d`Etudes du Bouchet, Vert le Petit (France); and others
Publication Date:
OSTI Identifier:
28976
Resource Type:
Journal Article
Journal Name:
Genomics
Additional Journal Information:
Journal Volume: 16; Journal Issue: 2; Other Information: PBD: May 1993
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; HUMAN CHROMOSOME 13; GENETIC MAPPING; BIOLOGICAL MARKERS

Citation Formats

Bowcock, A M, Barnes, R I, Gerken, S C, Leppert, M, Shiang, R, Jabs, E W, Warren, A C, Antonarakis, S, Retief, A E, and Vergnaud, G. The CEPH consortium linkage map of human chromosome 13. United States: N. p., 1993. Web. doi:10.1006/geno.1993.1215.
Bowcock, A M, Barnes, R I, Gerken, S C, Leppert, M, Shiang, R, Jabs, E W, Warren, A C, Antonarakis, S, Retief, A E, & Vergnaud, G. The CEPH consortium linkage map of human chromosome 13. United States. https://doi.org/10.1006/geno.1993.1215
Bowcock, A M, Barnes, R I, Gerken, S C, Leppert, M, Shiang, R, Jabs, E W, Warren, A C, Antonarakis, S, Retief, A E, and Vergnaud, G. 1993. "The CEPH consortium linkage map of human chromosome 13". United States. https://doi.org/10.1006/geno.1993.1215.
@article{osti_28976,
title = {The CEPH consortium linkage map of human chromosome 13},
author = {Bowcock, A M and Barnes, R I and Gerken, S C and Leppert, M and Shiang, R and Jabs, E W and Warren, A C and Antonarakis, S and Retief, A E and Vergnaud, G},
abstractNote = {The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158, 203, and 178cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM. 76 refs., 3 figs., 5 tabs.},
doi = {10.1006/geno.1993.1215},
url = {https://www.osti.gov/biblio/28976}, journal = {Genomics},
number = 2,
volume = 16,
place = {United States},
year = {Sat May 01 00:00:00 EDT 1993},
month = {Sat May 01 00:00:00 EDT 1993}
}