Structural and degradation studies of a biocompatible Zn-L-tartrate metal–organic framework

Journal Article · Fri May 15 00:00:00 EDT 2015 · Journal of Solid State Chemistry

DOI:https://doi.org/10.1016/J.JSSC.2014.11.028· OSTI ID:22475577

Palǒić, Ana; Puškarić, Andreas ^[1]; Mazaj, Matjaž ^[2]; Žunkoviǒ, Emanuela; Logar, Nataša Zabukovec ^[2]; Bronić, Josip ^[1]

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1. Ruđer Bošković Institute, Bijenička 54, 10000 Zagreb (Croatia)
2. National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia)

New anhydrous Zn-L-tratrate was synthesized under hydrothermal conditions. Crystal structure which was solved by powder X-ray diffraction data from monoclinic unit cell (I{sub 2}, a=11.7557(1), b=9.0319(1), c=5.0750(1), β=91.920(1)) consists of the three-dimensional framework where each Zn atom coordinates four tartrate ligands in distorted octahedral geometry. Due to its biocompatible components, the degradation of material was studied in aqueous media under different pH values (pH=1–7) and in the simulated body fluid (pH=7.4) performed by the measurement of the released Zn{sup 2+} concentrations at thermostatic conditions (37 °C). The results showed that under acidic conditions approximately 60% of Zn{sup 2+} is released from the investigated material after 6 h of degradation process. With the increase of the solution’s pH, the rate of degradation gradually decreases. XRD and SEM analyses indicate that in aqueous media the compound slowly disintegrates and does not undergo hydrolysis process regardless of pH. Biocompatibility of the compound and its controllable rate of degradation even in acid conditions open its potential use in the fields of bio-applications. - Graphical abstract: The degradation kinetics of Zn-L-tar MOF material in aqueous media at different pH conditions. - Highlights: • Anhydrous chiral Zn-L-tratrate was synthesized under hydrothermal conditions. • 3-D framework consists of Zn atoms, each chelating four tartrate ligands. • Degradation of material was studied in aqueous media at different pH values. • The compound disintegrates in controllable manner in aqueous solutions. • The rate compound degradation is increasing with increased acidity of solution.

• OSTI ID: 22475577
• Journal Information: Journal of Solid State Chemistry, Vol. 225; Other Information: Copyright (c) 2014 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0022-4596
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
AQUEOUS SOLUTIONS
BODY FLUIDS
CARBOXYLIC ACID ESTERS
CHELATING AGENTS
CHIRALITY
CONCENTRATION RATIO
HYDROLYSIS
HYDROTHERMAL SYNTHESIS
LIGANDS
MONOCLINIC LATTICES
PH VALUE
POWDERS
SCANNING ELECTRON MICROSCOPY
TAR
X-RAY DIFFRACTION
ZINC COMPOUNDS
ZINC IONS