Regional Radiation Pneumonitis After SIRT of a Subcapsular Liver Metastasis: What is the Effect of Direct Beta Irradiation?

Journal Article · Sat Aug 15 00:00:00 EDT 2015 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-014-1015-X· OSTI ID:22469883

Dobrocky, Tomas ^[1]; Fuerstner, Markus; Klaeser, Bernd ^[2]; Lopez-Benitez, Ruben ^[1]; Kara, Levent ^[1]

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1. University of Bern, Department of Interventional, Pediatric and Diagnostic Radiology, Inselspital, University Hospital (Switzerland)
2. University of Bern, Department of Nuclear Medicine, Inselspital, University Hospital (Switzerland)

We herein present a patient undergoing selective internal radiation therapy with an almost normal lung shunt fraction of 11.5 %, developing histologically proven radiation pneumonitis. Due to a predominance of pulmonary consolidations in the right lower lung and its proximity to a large liver metastases located in the dome of the right liver lobe a Monte Carlo simulation was performed to estimate the effect of direct irradiation of the lung parenchyma. According to our calculations direct irradiation seems negligible and RP is almost exclusively due to ectopic draining of radioactive spheres.

• OSTI ID: 22469883
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 38, Issue 4; Other Information: Copyright (c) 2015 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BYPASSES
COMPUTERIZED SIMULATION
IRRADIATION
LIVER
LUNGS
METASTASES
MONTE CARLO METHOD
PATIENTS
PNEUMONITIS
RADIOTHERAPY