Leisure time activities related to carcinogen exposure and lung cancer risk in never smokers. A case-control study

Journal Article · Tue Jul 15 00:00:00 EDT 2014 · Environmental Research

DOI:https://doi.org/10.1016/J.ENVRES.2014.03.027· OSTI ID:22447521

Ruano-Ravina, Alberto ^[1]; García-Lavandeira, José Antonio ^[1]; Torres-Durán, María ^[1]; Prini-Guadalupe, Luciana ^[1]; Parente-Lamelas, Isaura ^[2]; Leiro-Fernández, Virginia ^[3]; Montero-Martínez, Carmen ^[4]; González-Barcala, Francisco Javier; Golpe-Gómez, Antonio ^[5]; Martínez, Cristina ^[6]; Castro-Añón, Olalla ^[7]; Mejuto-Martí, María José ^[8]; others, and

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1. Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela (Spain)
2. Service of Neumology, Ourense Hospital Complex, Ourense (Spain)
3. Service of Neumology, University Hospital Complex of Vigo, Vigo (Spain)
4. Service of Neumology, University Hospital Complex of A Coruña, Coruña (Spain)
5. Service of Neumology, Santiago de Compostela University Clinic Hospital, Santiago de Compostela (Spain)
6. National Institute of Silicosis, University Hospital of Asturias, Oviedo, Asturias (Spain)
7. Service of Neumology, Hospital Lucus Augusti, Lugo (Spain)
8. Service of Neumology, Hospital Arquitecto Marcide, Ferrol (Spain)

We aim to assess the relationship between leisure time activities related to exposure to carcinogenic substances and lung cancer risk in a hospital-based case-control study performed in never smokers. We included never smoking cases with anatomopathologically confirmed lung cancer and never smoking controls undergoing trivial surgery, at 8 Spanish hospitals. The study was conducted between January 2011 and June 2013. Participants were older than 30 and had no previous neoplasms. All were personally interviewed focusing on lifestyle, environmental tobacco smoke exposure, occupational history and leisure time activities (including duration of such activities). Results were analyzed through logistic regression and adjusted also by residential radon and education level. We included 513 never smokers, 191 cases and 322 controls. The OR for those performing the studied leisure time activities was 1.43 (95%CI 0.78–2.61). When we restricted the analysis to those performing do-it-yourself activities for more than 10 years the OR was 2.21 (95%CI 0.93–5.27). Environmental tobacco smoke exposure did not modify this association. The effect for the different lung cancer histological types was very close to significance for adenocarcinoma but only when these activities were performed for more than 10 years. We encourage health professionals to recommend protective measures for those individuals while performing these hobbies to reduce the risk of lung cancer. - Highlights: • Some leisure time activities are associated with the exposure to carcinogenic substances. • These activities are model-making, painting (artistic or not), furniture refinishing or wood working. • Few studies have assessed lung cancer risk due to these hobbies and none in never-smokers. • Leisure activities related to exposure to carcinogenic substances present higher lung cancer risk. • The risk is higher when these activities are performed for more than 10 years.

• OSTI ID: 22447521
• Journal Information: Environmental Research, Vol. 132; Other Information: Copyright (c) 2014 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0013-9351
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
54 ENVIRONMENTAL SCIENCES
CARCINOGENS
CARCINOMAS
CONTROL
CULTURAL OBJECTS
EDUCATION
FOCUSING
HAZARDS
HOSPITALS
LEISURE TIME ACTIVITIES
LUNGS
RADON
SPAIN
SURGERY
TOBACCO SMOKES
WOOD