Optimization of Radiation Therapy Techniques for Prostate Cancer With Prostate-Rectum Spacers: A Systematic Review

Journal Article · Wed Oct 01 00:00:00 EDT 2014 · International Journal of Radiation Oncology, Biology and Physics

DOI:https://doi.org/10.1016/J.IJROBP.2014.06.044· OSTI ID:22423811

Mok, Gary ^[1]; Benz, Eileen ^[1]; Vallee, Jean-Paul ^[2]; Miralbell, Raymond ^[1]; Zilli, Thomas ^[1]

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1. Department of Radiation Oncology, Geneva University Hospital, Geneva (Switzerland)
2. Department of Radiology, Geneva University Hospital, Geneva (Switzerland)

Dose-escalated radiation therapy for localized prostate cancer improves disease control but is also associated with worse rectal toxicity. A spacer placed between the prostate and rectum can be used to displace the anterior rectal wall outside of the high-dose radiation regions and potentially minimize radiation-induced rectal toxicity. This systematic review focuses on the published data regarding the different types of commercially available prostate-rectum spacers. Dosimetric results and preliminary clinical data using prostate-rectum spacers in patients with localized prostate cancer treated by curative radiation therapy are compared and discussed.

• OSTI ID: 22423811
• Journal Information: International Journal of Radiation Oncology, Biology and Physics, Vol. 90, Issue 2; Other Information: Copyright (c) 2014 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0360-3016
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
COMPARATIVE EVALUATIONS
NEOPLASMS
OPTIMIZATION
PATIENTS
PROSTATE
RADIATION DOSES
RADIOTHERAPY
RECTUM
REVIEWS
SPACERS
TOXICITY