Measurement of the temperature dependence of Young's modulus of cartilage by phase-sensitive optical coherence elastography
- Department of Biomedical Engineering, University of Houston, Houston, Texas (United States)
- Department of Physics, M.V. Lomonosov Moscow State University (Russian Federation)
- Institute of Laser and Information Technologies, Russian Academy of Sciences, Troitsk, Moscow Region (Russian Federation)
The development of an effective system to monitor the changes in the elastic properties of cartilage tissue with increasing temperature in laser reconstruction is an urgent practical task. In this paper, the use of phase-sensitive optical coherence elastography for detection of elastic waves in the sample has allowed Young's modulus of cartilage tissue to be measured directly during heating. Young's modulus was calculated from the group velocity of propagation of elastic waves excited by means of a system supplying focused air pulses. The measurement results are in agreement with the results of measurements of the modulus of elasticity under mechanical compression. The technique developed allows for noninvasive measurements; its development is promising for the use in vivo. (laser biophotonics)
- OSTI ID:
- 22395825
- Journal Information:
- Quantum Electronics (Woodbury, N.Y.), Vol. 44, Issue 8; Other Information: Country of input: International Atomic Energy Agency (IAEA); ISSN 1063-7818
- Country of Publication:
- United States
- Language:
- English
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