Combining X-ray and electron-microscopy data to solve crystal structures
Journal Article
·
· Acta Crystallographica. Section D: Biological Crystallography
- Laboratoire de Microscopie Electronique Structurale, Institut de Biologie Structurale Jean-Pierre Ebel, 41 Rue Jules Horowitz, F-38027 Grenoble (France)
Overview and examples of combined use of X-ray and electron-microscopy data. Low-resolution electron-microscopy reconstructions can be used as search models in molecular replacement or may be combined with existing monomeric structures in order to produce multimeric models suitable for molecular replacement. The technique is described in the case of viral and subviral particles as well as in the case of oligomeric proteins.
- OSTI ID:
- 22347685
- Journal Information:
- Acta Crystallographica. Section D: Biological Crystallography, Vol. 64, Issue Pt 1; Other Information: PMCID: PMC2394810; PUBLISHER-ID: ba5118; PMID: 18094469; OAI: oai:pubmedcentral.nih.gov:2394810; Copyright (c) International Union of Crystallography 2008; This is an open-access article distributed under the terms described at http://journals.iucr.org/services/termsofuse.html.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0907-4449
- Country of Publication:
- Denmark
- Language:
- English
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