Synthesis, characterization and antibacterial study of tripodal tris-(N-benzoylthioureido)ethylamine
- School of Chemical Sciences and Food Technology, Faculty of Science and Technology, University Kebangsaan Malaysia, 43000, Bangi, Selangor (Malaysia)
- School of Biosciences and Biotechnology, Faculty of Science and Technology, University Kebangsaan Malaysia, 43000, Bangi, Selangor (Malaysia)
A new tripodal tris-(N-benzoylthiouredoethyl)amine has been successfully synthesized and characterized by spectroscopic technique such as FTIR, ESI MS, {sup 1}H and {sup 13}C NMR. The microanalysis data is in a good agreement with the expected molecular formula. The {sup 1}H NMR chemical shift for both amide and thioamide proton are at lower field than their normal value indicates the presence of the hydrogen bond between the carbonyl oxygen atom and thioamide hydrogen. This is possible when the benzoyl group adopt a trans configuration againts thione group along the C-N bond. The compound has been tested for antibacterial activity against three selected bacteria namely Staphylococcus aureus, Proteus vulgaris and Pseudomanas aeroginosa but there is no significant activities observed.
- OSTI ID:
- 22308318
- Journal Information:
- AIP Conference Proceedings, Vol. 1614, Issue 1; Conference: 2014 UKM FST postgraduate colloquium, Selangor (Malaysia), 9-11 Apr 2014; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
- Country of Publication:
- United States
- Language:
- English
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