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Title: Source localization of brain activity using helium-free interferometer

Journal Article · · Applied Physics Letters
DOI:https://doi.org/10.1063/1.4880097· OSTI ID:22300119
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  1. Institute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich, Jülich (Germany)
  2. Peter Grünberg Institute (PGI-5), Forschungszentrum Jülich, Jülich (Germany)

To detect extremely small magnetic fields generated by the human brain, currently all commercial magnetoencephalography (MEG) systems are equipped with low-temperature (low-T{sub c}) superconducting quantum interference device (SQUID) sensors that use liquid helium for cooling. The limited and increasingly expensive supply of helium, which has seen dramatic price increases recently, has become a real problem for such systems and the situation shows no signs of abating. MEG research in the long run is now endangered. In this study, we report a MEG source localization utilizing a single, highly sensitive SQUID cooled with liquid nitrogen only. Our findings confirm that localization of neuromagnetic activity is indeed possible using high-T{sub c} SQUIDs. We believe that our findings secure the future of this exquisitely sensitive technique and have major implications for brain research and the developments of cost-effective multi-channel, high-T{sub c} SQUID-based MEG systems.

OSTI ID:
22300119
Journal Information:
Applied Physics Letters, Vol. 104, Issue 21; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0003-6951
Country of Publication:
United States
Language:
English