Synchrotron radiation imaging is a powerful tool to image brain microvasculature
- Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008 (China)
- Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China)
Synchrotron radiation (SR) imaging is a powerful experimental tool for micrometer-scale imaging of microcirculation in vivo. This review discusses recent methodological advances and findings from morphological investigations of cerebral vascular networks during several neurovascular pathologies. In particular, it describes recent developments in SR microangiography for real-time assessment of the brain microvasculature under various pathological conditions in small animal models. It also covers studies that employed SR-based phase-contrast imaging to acquire 3D brain images and provide detailed maps of brain vasculature. In addition, a brief introduction of SR technology and current limitations of SR sources are described in this review. In the near future, SR imaging could transform into a common and informative imaging modality to resolve subtle details of cerebrovascular function.
- OSTI ID:
- 22250979
- Journal Information:
- Medical Physics, Vol. 41, Issue 3; Other Information: (c) 2014 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-2405
- Country of Publication:
- United States
- Language:
- English
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