Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases

Journal Article · Sun Dec 15 00:00:00 EST 2013 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-013-0690-3· OSTI ID:22207958

Ricke, Jens; Grosser, Oliver; Amthauer, Holger ^[1]

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1. Universitaetsklinikum Magdeburg AoeR, Klinik fuer Radiologie und Nuklearmedizin (Germany)

We report successful Y90-radioembolization of the lung applying Y90-resin microspheres via the bronchial artery in two patients with diffuse colorectal and renal cancer metastases, respectively. The deposition of radioactive Y90-resin-microspheres was technically feasible and resulted in a reasonable absorbed dose in the tumors. However, open questions remain regarding dosimetry and safe dose exposure to the lung. The technique warrants thorough investigation before clinical use. A Phase I trial to evaluate safety and preliminary efficacy is under preparation.

• OSTI ID: 22207958
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 36, Issue 6; Other Information: Copyright (c) 2013 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ABSORBED RADIATION DOSES
ARTERIES
DOSIMETRY
KIDNEYS
LUNGS
METASTASES
MICROSPHERES
NEOPLASMS
PATIENTS
YTTRIUM 90
RADIOEMBOLIZATION