Impact of MLC leaf width on the quality of the dose distribution in partial breast irradiation
- Physical Sciences, Peter MacCallum Cancer Centre, St. Andrew's Place, East Melbourne, Victoria 3002 (Australia)
- Radiation Therapy Services, Peter MacCallum Cancer Centre, St. Andrew's Place, East Melbourne, Victoria 3002 (Australia)
- Division of Radiation Oncology, Peter MacCallum Cancer Centre, St. Andrew's Place, East Melbourne, Victoria 3002 and University of Melbourne, Parkville, Victoria (Australia)
Partial-breast irradiation (PBI) aims to limit the target volume for radiotherapy in women with early breast cancer after partial mastectomy to the region at highest risk of local recurrence, the tumor bed. Multileaf collimators are used to achieve conformal radiation beam portals required for PBI. Narrower leaf widths are generally assumed to allow more conformal shaping of beam portals around irregularly shaped target volumes. The aim was to compare 5-mm and 10-mm leaf widths for patients previously treated using PBI and assess subsequent planning target volume (PTV) coverage and organ at risk (OAR) doses for 16 patients. Several plans (5-mm leaf width or 10-mm leaf width) were generated for each patient using the original treated plan as the basis for attempts at further optimization. Alternating between different leaf widths found no significant difference in terms of overall PTV coverage and OAR doses between treatment plans. Optimization of the original treated plan allowed a small decrease in ipsilateral breast dose, which was offset by a lower PTV minimum. No significant dosimetric difference was found to support an advantage of 5-mm over 10-mm leaf width in this setting.
- OSTI ID:
- 22130376
- Journal Information:
- Medical Dosimetry, Vol. 37, Issue 1; Other Information: Copyright (c) 2012 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0958-3947
- Country of Publication:
- United States
- Language:
- English
Similar Records
Treatment planning strategy for whole-brain radiotherapy with hippocampal sparing and simultaneous integrated boost for multiple brain metastases using intensity-modulated arc therapy
A Comparison of Volumetric Modulated Arc Therapy and Conventional Intensity-Modulated Radiotherapy for Frontal and Temporal High-Grade Gliomas