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Title: Digital optical phase conjugation of fluorescence in turbid tissue

Abstract

We demonstrate a method for phase conjugating fluorescence. Our method, called reference free digital optical phase conjugation, can conjugate extremely weak, incoherent optical signals. It was used to phase conjugate fluorescent light originating from a bead covered with 0.5 mm of light-scattering tissue. The phase conjugated beam refocuses onto the bead and causes a local increase of over two orders of magnitude in the light intensity. Potential applications are in imaging, optical trapping, and targeted photochemical activation inside turbid tissue.

Authors:
; ;  [1]
  1. Department of Electrical Engineering, California Institute of Technology, Pasadena, California (United States)
Publication Date:
OSTI Identifier:
22089389
Resource Type:
Journal Article
Journal Name:
Applied Physics Letters
Additional Journal Information:
Journal Volume: 101; Journal Issue: 8; Other Information: (c) 2012 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0003-6951
Country of Publication:
United States
Language:
English
Subject:
74 ATOMIC AND MOLECULAR PHYSICS; BEAMS; FLUORESCENCE; LIGHT SCATTERING; PHOTOCHEMISTRY; RADIATION PRESSURE; TRAPPING; TURBIDITY; VISIBLE RADIATION

Citation Formats

Vellekoop, Ivo M., Meng, Cui, and Changhuei, Yang. Digital optical phase conjugation of fluorescence in turbid tissue. United States: N. p., 2012. Web. doi:10.1063/1.4745775.
Vellekoop, Ivo M., Meng, Cui, & Changhuei, Yang. Digital optical phase conjugation of fluorescence in turbid tissue. United States. https://doi.org/10.1063/1.4745775
Vellekoop, Ivo M., Meng, Cui, and Changhuei, Yang. 2012. "Digital optical phase conjugation of fluorescence in turbid tissue". United States. https://doi.org/10.1063/1.4745775.
@article{osti_22089389,
title = {Digital optical phase conjugation of fluorescence in turbid tissue},
author = {Vellekoop, Ivo M. and Meng, Cui and Changhuei, Yang},
abstractNote = {We demonstrate a method for phase conjugating fluorescence. Our method, called reference free digital optical phase conjugation, can conjugate extremely weak, incoherent optical signals. It was used to phase conjugate fluorescent light originating from a bead covered with 0.5 mm of light-scattering tissue. The phase conjugated beam refocuses onto the bead and causes a local increase of over two orders of magnitude in the light intensity. Potential applications are in imaging, optical trapping, and targeted photochemical activation inside turbid tissue.},
doi = {10.1063/1.4745775},
url = {https://www.osti.gov/biblio/22089389}, journal = {Applied Physics Letters},
issn = {0003-6951},
number = 8,
volume = 101,
place = {United States},
year = {Mon Aug 20 00:00:00 EDT 2012},
month = {Mon Aug 20 00:00:00 EDT 2012}
}