Results from the first preclinical CT scanner with grating based phase contrast and a rotating gantry

Journal Article · Tue Jul 31 00:00:00 EDT 2012 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4742281· OSTI ID:22069160

Bech, Martin; Tapfer, Arne; Velroyen, Astrid; Yaroshenko, Andre; Pauwels, Bart; Bruyndonckx, Peter; Xuan, Liu; Sasov, Alexander; Mohr, Juergen; Walter, Marco; Pfeiffer, Franz ^[1]; Bruker microCT, 2550 Kontich ^[2]; Microworks GmbH, 76137 Karlsruhe ^[3]

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1. Department of Physics, Technische Universitaetet Muenchen, 85748 Garching (Germany) and Medical Radiation Physics, Lund University, 22185 Lund (Germany)
2. Belgium
3. Germany

After successful demonstrations of soft-tissue phase-contrast imaging with grating interferometers at synchrotron radiation sources and at laboratory based x-ray tubes, a first preclinical CT scanner with grating based phase contrast imaging modality has been constructed. The rotating gantry is equipped with a three-grating interferometer, a 50 watt tungsten anode source and a Hamamatsu flat panel detector. The total length of the interferometer is 45 cm, and the bed of the scanner is optimized for mice, with a scanning diameter of 35 mm. From one single scan both phase-contrast and standard attenuation based tomography can be attained, providing an overall gain in image contrast.

• OSTI ID: 22069160
• Journal Information: AIP Conference Proceedings, Vol. 1466, Issue 1; Conference: International workshop on X-ray and neutron phase imaging with gratings, Tokyo (Japan), 5-7 Mar 2012; Other Information: (c) 2012 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
60 APPLIED LIFE SCIENCES
ANIMAL TISSUES
ANODES
DIFFRACTION GRATINGS
GAIN
IMAGE PROCESSING
IMAGES
INTERFEROMETERS
MICE
PHOTON COMPUTED TOMOGRAPHY
SYNCHROTRON RADIATION SOURCES
TUNGSTEN
X RADIATION
X-RAY TUBES