Radiotherapy for Liver Metastases: A Review of Evidence
Journal Article
·
· International Journal of Radiation Oncology, Biology and Physics
- Department of Oncology, Aarhus University Hospital, Aarhus (Denmark)
- Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, Ontario (Canada)
- Radiation Oncology, Sir Charles Gairdner Hospital, Perth (Australia)
- Department of Oncology, University of Western Ontario, London, Ontario (Canada)
- Department of Radiation Oncology, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam (Netherlands)
- Department of Radiation Oncology, University of Colorado Comprehensive Cancer Center, Aurora, CO (United States)
- Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY (United States)
- Department of Radiation Oncology, University of Florida, Gainesville, FL (United States)
Over the past decade, there has been an increasing use of radiotherapy (RT) for the treatment of liver metastases. Most often, ablative doses are delivered to focal liver metastases with the goal of local control and ultimately improving survival. In contrast, low-dose whole-liver RT may be used for the palliation of symptomatic diffuse metastases. This review examines the available clinical data for both approaches. The review found that RT is effective both for local ablation of focal liver metastases and for palliation of patients with symptomatic liver metastases. However, there is a lack of a high level of evidence from randomized clinical trials.
- OSTI ID:
- 22056086
- Journal Information:
- International Journal of Radiation Oncology, Biology and Physics, Vol. 82, Issue 3; Other Information: Copyright (c) 2012 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0360-3016
- Country of Publication:
- United States
- Language:
- English
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