Intracavitary in vivo dosimetry based on multichannel fiber-coupled radioluminescence and optically stimulated luminescence of Al{sub 2}O{sub 3}:C

Conference · Fri Jul 01 00:00:00 EDT 2011

DOI:https://doi.org/10.1109/ANIMMA.2011.6172964· OSTI ID:22039900

Spasic, E; Magne, S ^[1]; Aubineau-Laniece, I; De Carlan, L ^[2]; Malet, C; Ginestet, C ^[3]; Ferdinand, P ^[1]

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1. CEA, LIST, Laboratoire de Mesures Optiques, F-91191 Gif-sur-Yvette (France)
2. CEA, LIST, Laboratoire National Henri Becquerel, F-91191 Gif-sur-Yvette (France)
3. Centre Leon-Berard, Service de Physique, 28 rue Laennec, F-69373 Lyon (France)

Fiber Optic Dosimetric Catheters (FODCs) composed of chains of alumina crystals are investigated by the CEA LIST within the French ANR-INTRADOSE Project in the purpose of intracavitary in vivo dosimetry (IVD) during Brachytherapy (BT) with iridium sources and Intensity-Modulated Radiation Therapy (IMRT) with linear accelerators. A dedicated process involving PMMA fibers, cast altogether forming hexagonal bundle, is demonstrated. Optically Stimulated Luminescence (OSL) signals are recorded on-line after irradiation and absorbed doses are compared to planned dose distribution. Real-time dose measurements may also be performed by recording the Radioluminescence (RL), spontaneously emitted by the crystals during irradiation. In this case, a correction method is implemented to correct for stem effect influence (Cerenkov and scintillation generated within the fibers). For BT, the dual-fiber subtraction method is used (using a reference fiber) whereas the time discrimination method is used for IMRT. The experimental dose distribution leads to an underestimation of the source-sensor distance presumably due to energy dependence of the alumina crystal at low photon energy. At the time being, Monte-Carlo modeling of the FODC is performed with the aim to estimate this energy dependence and finally correct for it. Finally, metrological and preclinical validations are still running at Centre Leon Berard (Lyon (France)) in the purpose of checking the compliance of the FODC prototypes with treatment specifications and medical constraints. (authors)

• OSTI ID: 22039900
• Resource Relation: Conference: ANIMMA 2011: 2. International Conference on Advancements in Nuclear Instrumentation, Measurement Methods and their Applications, Ghent (Belgium), 6-9 Jun 2011; Other Information: Country of input: France; 16 refs.; IEEE Catalog Number: CFP1124I-CDR
• Country of Publication: United States
• Language: English

Related Subjects

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
62 RADIOLOGY AND NUCLEAR MEDICINE
ALUMINIUM OXIDES
BRACHYTHERAPY
CHERENKOV RADIATION
CRYSTALS
DOSIMETRY
ENERGY DEPENDENCE
FIBER OPTICS
IN VIVO
IRIDIUM
LINEAR ACCELERATORS
MONTE CARLO METHOD
PHOTONS
PMMA
RADIATION DOSE DISTRIBUTIONS
RADIOLUMINESCENCE
SCINTILLATIONS
SENSORS