Application of X-ray synchrotron microscopy instrumentation in biology

Conference · Fri Jul 01 00:00:00 EDT 2011

DOI:https://doi.org/10.1109/ANIMMA.2011.6172972· OSTI ID:22039823

Gasperini, F M ^[1]; Pereira, G R ^[2]; Granjeiro, J M ^[3]; Calasans-Maia, M D ^[4]; Rossi, A M ^[5]; Perez, C A ^[6]; Lopes, R T; Lima, I ^[7]

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1. Medical Science Program, Fluminense Federal Univ., Niteroi (Brazil)
2. Dept. of Metallurgical and Materials Engineering, Federal Univ. of Rio de Janeiro (Brazil)
3. Molecular and Cell Biology Dept., Fluminense Federal Univ., Niteroi, Rio de Janeiro (Brazil)
4. Oral Surgery Dept., Fluminense Federal Univ., Niteroi, Rio de Janeiro (Brazil)
5. Biomaterials Laboratory, Brazilian Center of Physics Research, Rio de Janeiro (Brazil)
6. Brazilian Synchrotron Laboratory, Campinas, Sao Paulo (Brazil)
7. Nuclear Engineering Laboratory, Federal Univ. of Rio de Janeiro (Brazil)

X-ray micro-fluorescence imaging technique has been used as a significant tool in order to investigate minerals contents in some kinds of materials. The aim of this study was to evaluate the elemental distribution of calcium and zinc in bone substitute materials (nano-hydroxyapatite spheres) and cortical bones through X-Ray Micro-fluorescence analysis with the increment of Synchrotron Radiation in order to evaluate the characteristics of the newly formed bone and its interface, the preexisting bone and biomaterials by the arrangement of collagen fibers and its birefringence. The elemental mapping was carried out at Brazilian Synchrotron Light Laboratory, Campinas - Sao Paulo, Brazil working at D09-XRF beam line. Based on this study, the results suggest that hydroxyapatite-based biomaterials are biocompatible, promote osteo-conduction and favored bone repair. (authors)

• OSTI ID: 22039823
• Resource Relation: Conference: ANIMMA 2011: 2. International Conference on Advancements in Nuclear Instrumentation, Measurement Methods and their Applications, Ghent (Belgium), 6-9 Jun 2011; Other Information: Country of input: France; 16 refs.; IEEE Catalog Number: CFP1124I-CDR
• Country of Publication: United States
• Language: English

Related Subjects

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
60 APPLIED LIFE SCIENCES
APATITES
BEAMS
BIOLOGICAL MATERIALS
BIREFRINGENCE
CALCIUM
COLLAGEN
FIBERS
HYDROXY COMPOUNDS
MAPPING
MICROSCOPY
REPAIR
SKELETON
SPATIAL DISTRIBUTION
SYNCHROTRON RADIATION
SYNCHROTRONS
X RADIATION
X-RAY FLUORESCENCE ANALYSIS
ZINC