Acute Thrombocytopenia: An Unusual Complication Occurring After Drug-Eluting Microspheres Transcatheter Hepatic Chemoembolization

Journal Article · Tue Feb 15 00:00:00 EST 2011 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-010-9983-Y· OSTI ID:21608737

Poggi, Guido ^[1]; Quaretti, Pietro ^[2]; Montagna, Benedetta; Sottotetti, Federico; Tagliaferri, Barbara; Pozzi, Emma; Amatu, Alessio; Pagella, Chiara; Bernardo, Giovanni ^[1]

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1. Istituto Scientifico di Pavia, Department of Oncology, IRCCS Fondazione S. Maugeri (Italy)
2. IRCCS Policlinico San Matteo, Department of Interventional Radiology (Italy)

Image-guided transcatheter hepatic chemoembolization (TACE) is accepted worldwide as an effective treatment for patients with unresectable hepatocellular carcinoma and liver metastases from neuroendocrine tumors, colorectal carcinomas, and uveal melanomas. Although the technique is relatively safe, it has been associated with several complications. We report the cases of two patients with colorectal liver metastases who developed acute thrombocytopenia a few hours after TACE. To our knowledge, acute thrombocytopenia occurring after TACE with drug-eluting microspheres has not yet been reported. Here we discuss the hypothetical etiopathogenetic mechanisms.

• OSTI ID: 21608737
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 34, Issue 2; Other Information: DOI: 10.1007/s00270-010-9983-y; Copyright (c) 2011 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
DRUGS
HEPATOMAS
IMAGES
LIVER
MELANOMAS
METASTASES
PATIENTS
BODY
CARCINOMAS
DIGESTIVE SYSTEM
DISEASES
EPITHELIOMAS
GLANDS
NEOPLASMS
ORGANS