Spontaneous Liver Rupture After Treatment With Drug-Eluting Beads

Journal Article · Wed Feb 15 00:00:00 EST 2012 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-011-0145-7· OSTI ID:21608624

Wartenberg, M; Mottok, A ^[1]; Steger, U ^[2]; Goltz, J P; Hahn, D; Kickuth, R ^[3]

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1. University of Wuerzburg, Institute of Pathology (Germany)
2. University of Wuerzburg, Department of General, Visceral, Vascular, and Pediatric Surgery (Germany)
3. University of Wuerzburg, Institute of Radiology (Germany)

Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

• OSTI ID: 21608624
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 35, Issue 1; Other Information: DOI: 10.1007/s00270-011-0145-7; Copyright (c) 2012 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
DOXORUBICIN
EDEMA
HAZARDS
HEPATOMAS
LIVER
MALES
PATIENTS
RUPTURES
ANTIBIOTICS
ANTI-INFECTIVE AGENTS
ANTINEOPLASTIC DRUGS
BODY
CARCINOMAS
DIGESTIVE SYSTEM
DISEASES
DRUGS
FAILURES
GLANDS
NEOPLASMS
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
SYMPTOMS