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Title: Clinical Evaluation of an Immbolization System for Stereotactic Body Radiotherapy Using Helical Tomotherapy

Abstract

In this study, a clinical evaluation of the Body Pro-Lok{sup TM} System combined with the TomoTherapy megavoltage computed tomography (MVCT) was performed for lung and liver stereotactic body radiotherapy (SBRT) to reduce interfractional setup uncertainty. Twenty patients treated with 3-5 fractions of SBRT were analyzed retrospectively. The Body Pro-Lok{sup TM} system was used in both CT simulation and during patient treatment setup. Patients were immobilized with a vacuum cushion placed posteriorly over the thoracic region, an abdominal compression plate, and a knee and foot sponge. Pretreatment MVCT scans of the TomoTherapy HI-ART II unit were fused with the planning kVCT before delivery of each fraction to determine the interfractional setup error. A total of 84 shifts were analyzed to assess the interfractional setup accuracy. Results showed that the mean interfractional setup errors and standard deviations were -0.9 {+-} 3.1 mm, 1.2 {+-} 5.5 mm, and 6.5 {+-} 2.6 mm for lateral (IEC-X), longitudinal (IEC-Y), and vertical (IEC-Z) variations, respectively. The maximum motion was 17.1 mm in the longitudinal direction. When all 3 translational coordinates were analyzed, a mean composite displacement vector of 8.2 {+-} 2.0 mm (range 4.1-11.7 mm) was obtained for all patients. Based on the findings, image-guided SBRTmore » using the Body Pro-Lok{sup TM} system in conjunction with the MVCT of TomoTherapy is capable of minimizing interfractional setup error and improving treatment accuracy.« less

Authors:
; ; ; ;  [1]
  1. Department of Radiation Oncology, School of Medicine, Cancer Therapy and Research Center, University of Texas Health Science Center-San Antonio, San Antonio, TX (United States)
Publication Date:
OSTI Identifier:
21486899
Resource Type:
Journal Article
Journal Name:
Medical Dosimetry
Additional Journal Information:
Journal Volume: 36; Journal Issue: 2; Other Information: DOI: 10.1016/j.meddos.2010.02.003; PII: S0958-3947(10)00020-8; Copyright (c) 2011 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Journal ID: ISSN 0958-3947
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACCURACY; COMPUTERIZED TOMOGRAPHY; CT-GUIDED RADIOTHERAPY; ERRORS; EVALUATION; LIVER; LUNGS; MOTION; PATIENTS; BODY; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; GLANDS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RADIOTHERAPY; RESPIRATORY SYSTEM; THERAPY; TOMOGRAPHY

Citation Formats

Gutierrez, Alonso N., E-mail: gutierrezan@uthscsa.ed, Stathakis, Sotirios, Crownover, Richard, Esquivel, Carlos, Chengyu, Shi, and Papanikolaou, Niko. Clinical Evaluation of an Immbolization System for Stereotactic Body Radiotherapy Using Helical Tomotherapy. United States: N. p., 2011. Web. doi:10.1016/j.meddos.2010.02.003.
Gutierrez, Alonso N., E-mail: gutierrezan@uthscsa.ed, Stathakis, Sotirios, Crownover, Richard, Esquivel, Carlos, Chengyu, Shi, & Papanikolaou, Niko. Clinical Evaluation of an Immbolization System for Stereotactic Body Radiotherapy Using Helical Tomotherapy. United States. https://doi.org/10.1016/j.meddos.2010.02.003
Gutierrez, Alonso N., E-mail: gutierrezan@uthscsa.ed, Stathakis, Sotirios, Crownover, Richard, Esquivel, Carlos, Chengyu, Shi, and Papanikolaou, Niko. 2011. "Clinical Evaluation of an Immbolization System for Stereotactic Body Radiotherapy Using Helical Tomotherapy". United States. https://doi.org/10.1016/j.meddos.2010.02.003.
@article{osti_21486899,
title = {Clinical Evaluation of an Immbolization System for Stereotactic Body Radiotherapy Using Helical Tomotherapy},
author = {Gutierrez, Alonso N., E-mail: gutierrezan@uthscsa.ed and Stathakis, Sotirios and Crownover, Richard and Esquivel, Carlos and Chengyu, Shi and Papanikolaou, Niko},
abstractNote = {In this study, a clinical evaluation of the Body Pro-Lok{sup TM} System combined with the TomoTherapy megavoltage computed tomography (MVCT) was performed for lung and liver stereotactic body radiotherapy (SBRT) to reduce interfractional setup uncertainty. Twenty patients treated with 3-5 fractions of SBRT were analyzed retrospectively. The Body Pro-Lok{sup TM} system was used in both CT simulation and during patient treatment setup. Patients were immobilized with a vacuum cushion placed posteriorly over the thoracic region, an abdominal compression plate, and a knee and foot sponge. Pretreatment MVCT scans of the TomoTherapy HI-ART II unit were fused with the planning kVCT before delivery of each fraction to determine the interfractional setup error. A total of 84 shifts were analyzed to assess the interfractional setup accuracy. Results showed that the mean interfractional setup errors and standard deviations were -0.9 {+-} 3.1 mm, 1.2 {+-} 5.5 mm, and 6.5 {+-} 2.6 mm for lateral (IEC-X), longitudinal (IEC-Y), and vertical (IEC-Z) variations, respectively. The maximum motion was 17.1 mm in the longitudinal direction. When all 3 translational coordinates were analyzed, a mean composite displacement vector of 8.2 {+-} 2.0 mm (range 4.1-11.7 mm) was obtained for all patients. Based on the findings, image-guided SBRT using the Body Pro-Lok{sup TM} system in conjunction with the MVCT of TomoTherapy is capable of minimizing interfractional setup error and improving treatment accuracy.},
doi = {10.1016/j.meddos.2010.02.003},
url = {https://www.osti.gov/biblio/21486899}, journal = {Medical Dosimetry},
issn = {0958-3947},
number = 2,
volume = 36,
place = {United States},
year = {Fri Jul 01 00:00:00 EDT 2011},
month = {Fri Jul 01 00:00:00 EDT 2011}
}