Study of the influence of glucose on diffuse reflection of ultrashort laser pulses from a medium simulating a biological tissue
- M. V. Lomonosov Moscow State University, Faculty of Physics, Moscow (Russian Federation)
- University of Oulu, Optoelectronics and Measurements Techniques Laboratory (Finland)
The influence of glucose on the diffuse reflection of near-IR femtosecond laser radiation from single- and three-layer media simulating biological tissues is studied experimentally. Based on a 800-nm femtosecond Ti:sapphire laser emitting 40-fs pulses and a VUV Agat streak camera, a setup is built for time and spatially resolved detection of radiation diffusely reflected from the volume of a strongly scattering medium. A multichannel fibreoptic system is developed for detecting pulses simultaneously at several fixed distances between a radiation source and detector. It is shown that the peak intensity and total energy of detected pulses are sensitive to variations in the glucose concentration in the medium under study from 0 to 1000 mg dL{sup -1}. The relative sensitivity in our experiments achieved 0.030% mg dL{sup -1}. (biophotonics)
- OSTI ID:
- 21466816
- Journal Information:
- Quantum Electronics (Woodbury, N.Y.), Vol. 38, Issue 5; Other Information: DOI: 10.1070/QE2008v038n05ABEH013802; ISSN 1063-7818
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
GENERAL PHYSICS
DISTANCE
FAR ULTRAVIOLET RADIATION
GLUCOSE
LASER RADIATION
LASERS
PEAKS
PULSES
RADIATION DETECTION
RADIATION SOURCES
REFLECTION
SAPPHIRE
SCATTERING
SENSITIVITY
STREAK CAMERAS
ALDEHYDES
CAMERAS
CARBOHYDRATES
CORUNDUM
DETECTION
ELECTROMAGNETIC RADIATION
HEXOSES
MINERALS
MONOSACCHARIDES
ORGANIC COMPOUNDS
OXIDE MINERALS
RADIATIONS
SACCHARIDES
ULTRAVIOLET RADIATION