Synchrotron FTIR Imaging For The Identification Of Cell Types Within Human Tissues

Journal Article · Wed Feb 03 00:00:00 EST 2010 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.3326333· OSTI ID:21370975

Walsh, Michael J; Pounder, F Nell ^[1]; Nasse, Michael J ^[2]; Macias, Virgilia; Kajdacsy-Balla, Andre ^[3]; Hirschmugl, Carol ^[2]; Bhargava, Rohit ^[1]

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1. Beckman Institute, University of Illinois, 405 N Mathews Ave, Urbana, Il 61801 (United States)
2. University of Wisconsin-Milwaukee, Department of Physics, 1900 E. Kenwood Blvd., Milwaukee, WI, 53211 (United States)
3. Department of Pathology, University of Illinois at Chicago, 840 S. Wood St. Chicago, Il. 60612 (United States)

The use of synchrotron Fourier Transform Infrared spectroscopy (S-FTIR) has been shown to be a very promising tool for biomedical research. S-FTIR spectroscopy allows for the fast acquisition of infrared (IR) spectra at a spatial resolution approaching the IR diffraction limit. The development of the Infrared Environmental Imaging (IRENI) beamline at the Synchrotron Radiation Center (SRC) at the University of Wisconsin-Madison has allowed for diffraction limited imaging measurements of cells in human prostate and breast tissues. This has allowed for the identification of cell types within tissues that would otherwise not have been resolvable using conventional FTIR sources.

• OSTI ID: 21370975
• Journal Information: AIP Conference Proceedings, Vol. 1214, Issue 1; Conference: WIRMS 2009: 5. international workshop on infrared microscopy and spectroscopy with accelerator based sources, Alberta (Canada), 13-17 Sep 2009; Other Information: DOI: 10.1063/1.3326333; (c) 2010 American Institute of Physics; ISSN 0094-243X
• Country of Publication: United States
• Language: English

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