Hybrid quantitative simulation on the in-line phase-contrast x-ray imaging of three dimensional samples under actual clinic imaging parameters

Journal Article · Mon Jul 06 00:00:00 EDT 2009 · Applied Physics Letters

DOI:https://doi.org/10.1063/1.3162333· OSTI ID:21294179

Hong, Yu; Shensheng, Han ^[1]; Jianhui, Ding; Zhaoxia, Jiang; Weijun, Peng ^[2]

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1. Key Laboratory for Quantum Optics of CAS, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Science, Shanghai 201800 (China)
2. Department of Radiology, Fudan University, Shanghai Cancer Center, Shanghai 200032 (China)

A hybrid model combining Monte Carlo method with diffraction theory of wave optics has been developed and applied to quantitatively simulate the in-line diffractive phase-contrast x-ray imaging of three dimensional tissue samples under actual clinic imaging parameters. The primary microcosmic interactions of medical-energy x-ray within matter including photoabsorption, Compton scattering, and coherent scattering, have been taken into account in the Monte Carlo simulation. A diffraction processing based on Fresnel diffraction theory is carried out to simulate the macroscopic diffraction effect. A comparison with experiment results has also been performed.

• OSTI ID: 21294179
• Journal Information: Applied Physics Letters, Vol. 95, Issue 1; Other Information: DOI: 10.1063/1.3162333; (c) 2009 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0003-6951
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL RADIATION EFFECTS
BIOMEDICAL RADIOGRAPHY
COMPTON EFFECT
COMPUTERIZED SIMULATION
FRESNEL LENS
IMAGES
MONTE CARLO METHOD
THREE-DIMENSIONAL CALCULATIONS
X-RAY DIFFRACTION