Living tissue under treatment of cold plasma atmospheric jet

Journal Article · Mon Nov 03 00:00:00 EST 2008 · Applied Physics Letters

DOI:https://doi.org/10.1063/1.3020223· OSTI ID:21175700

Shashurin, A; Keidar, M; Bronnikov, S ^[1]; Jurjus, R A; Stepp, M A ^[2]

---

1. Department of Mechanical and Aerospace Engineering, School of Engineering and Applied Science, The George Washington University, Washington, District of Columbia 20052 (United States)
2. Department of Anatomy and Regenerative Biology, George Washington University Medical School, The George Washington University, Washington, District of Columbia 20052 (United States)

The interaction of the cold atmospheric plasma jet with fibroblast cells was studied. Plasma jet was initiated in the helium flow blowing through the syringe by application of high ac voltage to the discharge electrodes. The plasma jet had a length of 5 cm and a diameter of 1.5-2 mm in ambient air. Treatment of cells with plasma jet resulted in decreasing of cell migration rate, cell detachment, and appearance of ''frozen'' cells, while treatment with helium flow (no plasma) resulted in appearance of frozen cells only. A variety of cellular responses was explained by different intensities of treatment.

• OSTI ID: 21175700
• Journal Information: Applied Physics Letters, Vol. 93, Issue 18; Other Information: DOI: 10.1063/1.3020223; (c) 2008 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0003-6951
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
AIR
COLD PLASMA
ELECTRIC POTENTIAL
ELECTRODES
FIBROBLASTS
HELIUM
PATIENTS
PLASMA JETS