Validation of Supervised Automated Algorithm for Fast Quantitative Evaluation of Organ Motion on Magnetic Resonance Imaging
- Department of Radiation Oncology, Princess Margaret Hospital, Toronto, ON (Canada)
- GE Healthcare Canada, Mississauga, ON (Canada)
- Department of Radiation Physics, Princess Margaret Hospital, Toronto, ON (Canada)
- Department of Medical Imaging, University Health Network, Toronto, ON (Canada)
- Department of Biostatistics, Princess Margaret Hospital, Toronto, ON (Canada)
Purpose: To validate a correlation coefficient template-matching algorithm applied to the supervised automated quantification of abdominal-pelvic organ motion captured on time-resolved magnetic resonance imaging. Methods and Materials: Magnetic resonance images of 21 patients across four anatomic sites were analyzed. Representative anatomic points of interest were chosen as surrogates for organ motion. The point of interest displacements across each image frame relative to baseline were quantified manually and through the use of a template-matching software tool, termed 'Motiontrack.' Automated and manually acquired displacement measures, as well as the standard deviation of intrafraction motion, were compared for each image frame and for each patient. Results: Discrepancies between the automated and manual displacements of {>=}2 mm were uncommon, ranging in frequency of 0-9.7% (liver and prostate, respectively). The standard deviations of intrafraction motion measured with each method correlated highly (r = 0.99). Considerable interpatient variability in organ motion was demonstrated by a wide range of standard deviations in the liver (1.4-7.5 mm), uterus (1.1-8.4 mm), and prostate gland (0.8-2.7 mm). The automated algorithm performed successfully in all patients but 1 and substantially improved efficiency compared with manual quantification techniques (5 min vs. 60-90 min). Conclusion: Supervised automated quantification of organ motion captured on magnetic resonance imaging using a correlation coefficient template-matching algorithm was efficient, accurate, and may play an important role in off-line adaptive approaches to intrafraction motion management.
- OSTI ID:
- 21124376
- Journal Information:
- International Journal of Radiation Oncology, Biology and Physics, Vol. 71, Issue 4; Other Information: DOI: 10.1016/j.ijrobp.2007.11.021; PII: S0360-3016(07)04569-5; Copyright (c) 2008 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); ISSN 0360-3016
- Country of Publication:
- United States
- Language:
- English
Similar Records
Automatic tracking of arbitrarily shaped implanted markers in kilovoltage projection images: A feasibility study
Prostate position relative to pelvic bony anatomy based on intraprostatic gold markers and electronic portal imaging