GP IIb/IIIa Blockade During Peripheral Artery Interventions

Journal Article · Tue Jan 15 00:00:00 EST 2008 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-005-0266-Y· OSTI ID:21090708

Tepe, Gunnar; Wiskirchen, Jakub; Pereira, Philippe; Claussen, Claus D; Miller, Stephen ^[1]; Duda, Stephan H ^[2]

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1. University of Tuebingen, Department of Diagnostic Radiology (Germany)
2. The Jewish Hospital, Center for Diagnostic Radiology and Minimally Invasive Therapy (Germany)

The activation of the platelet GP IIb/IIIa receptor is the final and common pathway in platelet aggregation. By blocking this receptor, platelet aggregation can be inhibited independently of the stimulus prompted the targeting of this receptor. Several years ago, three drugs have been approved for coronary artery indications. Since that time, there is increasing evidence that GP IIb/IIIa receptor blockade might have also an important role in peripheral arterial intervention. This article summarizes the action and differences of GP Ilb/IIIa receptor inhibitors and its possible indication in peripheral arteries.

• OSTI ID: 21090708
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 31, Issue 1; Other Information: DOI: 10.1007/s00270-005-0266-y; Copyright (c) 2008 Springer Science+Business Media, LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
AGGLOMERATION
CORONARIES
DRUGS
RECEPTORS
STIMULI
VASCULAR DISEASES