Percutaneous Interventions in Radiation-Associated Coronary In-Stent Restenosis

Wexberg, P; Beran, G; Lang, I; Siostrzonek, P; Kirisits, C; Glogar, D; Gottsauner-Wolf, M

doi:10.1007/S00270-002-2644-Z

Title: Percutaneous Interventions in Radiation-Associated Coronary In-Stent Restenosis

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Abstract

This study was performed to evaluate the outcome of percutaneous revascularization in 'edge restenoses' developing after radioactive stent implantation in de novo and in-stentlesions. Twenty-one consecutive patients undergoing target lesion revascularization (TLR) at any follow-up after phosphorus-32 radioacttive stent implantation were included in this study. We assessed the incidence of death, myocardial infarction, repeated TLR and recurrent angina over the following 18 months. After 6 months, TLR rate was 28.6%, and no stent thromboses, deaths or Q-wave myocardial infarctions occurred. Among the patients with TLR there were significantly more subjects who had received a radioactive stent in a previous in-stent restenosis (66.7% vs. 0% in patients without second restenosis; P < 0.001), or who had received two radioactive stents (83.3% vs. 33.3%; P = 0.038).After 18 months, TLR rate was 33.3%, and two patients (9.5%) had died. Restenosis after intravascular radiotherapy can be safely treated by percutaneous interventional techniques, yielding an acceptable clinical result within 18 months.

Authors:

Wexberg, P; Beran, G; Lang, I; Siostrzonek, P ^[1]; Kirisits, C ^[2]; Glogar, D; Gottsauner-Wolf, M ^[1]

Division of Cardiology, Department of Internal Medicine II, University of Vienna (Austria)
Division of Medical Radiation Physics, Department of Radiotherapy and Radiobiology, University of Vienna (Austria)

Publication Date:: Tue Apr 15 00:00:00 EDT 2003

OSTI Identifier:: 21088401

Resource Type:: Journal Article

Journal Name:: Cardiovascular and Interventional Radiology

Additional Journal Information:: Journal Volume: 26; Journal Issue: 2; Other Information: DOI: 10.1007/s00270-002-2644-z; Copyright (c) 2003 Springer-Verlag New York, Inc.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; DEATH; MYOCARDIAL INFARCTION; PATIENTS; RADIOTHERAPY; VASCULAR DISEASES

Citation Formats


                    Wexberg, P, Beran, G, Lang, I, Siostrzonek, P, Kirisits, C, Glogar, D, and Gottsauner-Wolf, M. Percutaneous Interventions in Radiation-Associated Coronary In-Stent Restenosis.  United States: N. p., 2003. 
        Web.  doi:10.1007/S00270-002-2644-Z.

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                    Wexberg, P, Beran, G, Lang, I, Siostrzonek, P, Kirisits, C, Glogar, D, & Gottsauner-Wolf, M. Percutaneous Interventions in Radiation-Associated Coronary In-Stent Restenosis.  United States.  https://doi.org/10.1007/S00270-002-2644-Z

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                    Wexberg, P, Beran, G, Lang, I, Siostrzonek, P, Kirisits, C, Glogar, D, and Gottsauner-Wolf, M. 2003.  
        "Percutaneous Interventions in Radiation-Associated Coronary In-Stent Restenosis".  United States.  https://doi.org/10.1007/S00270-002-2644-Z.

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@article{osti_21088401,

  title        = {Percutaneous Interventions in Radiation-Associated Coronary In-Stent Restenosis},

  author       = {Wexberg, P and Beran, G and Lang, I and Siostrzonek, P and Kirisits, C and Glogar, D and Gottsauner-Wolf, M},

  abstractNote = {This study was performed to evaluate the outcome of percutaneous revascularization in 'edge restenoses' developing after radioactive stent implantation in de novo and in-stentlesions. Twenty-one consecutive patients undergoing target lesion revascularization (TLR) at any follow-up after phosphorus-32 radioacttive stent implantation were included in this study. We assessed the incidence of death, myocardial infarction, repeated TLR and recurrent angina over the following 18 months. After 6 months, TLR rate was 28.6%, and no stent thromboses, deaths or Q-wave myocardial infarctions occurred. Among the patients with TLR there were significantly more subjects who had received a radioactive stent in a previous in-stent restenosis (66.7% vs. 0% in patients without second restenosis; P < 0.001), or who had received two radioactive stents (83.3% vs. 33.3%; P = 0.038).After 18 months, TLR rate was 33.3%, and two patients (9.5%) had died. Restenosis after intravascular radiotherapy can be safely treated by percutaneous interventional techniques, yielding an acceptable clinical result within 18 months.},

  doi          = {10.1007/S00270-002-2644-Z},

  url          = {https://www.osti.gov/biblio/21088401},
  journal      = {Cardiovascular and Interventional Radiology},

  issn         = {0174-1551},

  number       = 2,

  volume       = 26,

  place        = {United States},

  year         = {Tue Apr 15 00:00:00 EDT 2003},

  month        = {Tue Apr 15 00:00:00 EDT 2003}

}

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